This Article  • Full text  • PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Contact me when this article is cited  Related Content  • Related article  • Similar articles in this journal  Topic Collections  • Granulomas  • Diagnosis  • Alert me on articles by topic

Arch Dermatol. 2003;139:657-662.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Diagnosis: Annular elastolytic giant cell granuloma (AEGCG).

MICROSCOPIC FINDINGS AND CLINICAL COURSE

On microscopic examination, the epidermis was unremarkable. In the middermis, many histiocytes, often multinucleated, were noted in association with fragmentation of the elastic fibers, which was more obvious in sections stained with orcein (Figure 4). Fragments of elastic fibers were engulfed by multinucleated giant cells. There was no necrobiosis or excessive mucopolysaccharide deposition.

Figure appears in full text version. Figure 4.

Based on the clinical and microscopic findings, the diagnosis of AEGCG was made. The patient was reassured about the benign nature of his condition and was offered the option of treatment with antimalarial agents, which he declined. On follow-up 1 year later, the eruption remained stable.

DISCUSSION

Annular elastolytic giant cell granuloma is a rare granulomatous disorder. O'Brien¹ initially called the disease actinic granuloma because of the occurrence of lesions on sun-exposed sites and their relation to actinically or heat-damaged skin. Subsequent authors, however, have questioned the proposed actinic pathogenesis of the disorder and . . . [Full Text of this Article]

RELATED ARTICLE

Large Annular Plaques on the Trunk and Arms—Quiz Case
Alexander J. Stratigos, Christina Antoniou, Katherine Limas, and Andreas D. Katsambas
Arch Dermatol. 2003;139(5):657-662.
EXTRACT | FULL TEXT