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Arch Dermatol. 2003;139:787-788.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

LIKE A DRIVER with one foot on the accelerator and the other on the brake, Tunnell et al¹ in this issue of the ARCHIVES explore aggressive pulsed dye laser treatment combined with aggressive skin cooling. Cryogen spray cooling (CSC) with a burst of -30°C liquid applied just before arrival of a laser pulse has been clearly shown to reduce the pain and risk of epidermal injury from pulsed dye laser treatment. Can very aggressive CSC protect against thermal injury from very aggressive laser treatment? The answer appears to be yes, but to a limited degree for pigmented skin and with the caveat that this study is limited to histologic observations made immediately after treatment in normal skin. For darkly pigmented skin (phototypes V and VI), there was little or no epidermal protection by aggressive CSC. But more important, the study raises important clinical issues.

The motivation for this study seems . . . [Full Text of this Article]

EPIDERMAL PROTECTION?


DERMAL PROTECTION?

BALANCING FIRE AND ICE

RELATED ARTICLE

Effects of Cryogen Spray Cooling and High Radiant Exposures on Selective Vascular Injury During Laser Irradiation of Human Skin
James W. Tunnell, David W. Chang, Carol Johnston, Jorge H. Torres, Charles W. Patrick, Jr, Michael J. Miller, Sharon L. Thomsen, and Bahman Anvari
Arch Dermatol. 2003;139(6):743-750.
ABSTRACT | FULL TEXT