Commentary on: Local treatments for cutaneous warts: systematic review
Gibbs S, Harvey I, Sterling J, Stark R
BMJ. 2002;325:461
Question: In immunocompetent children and adults, at what rate do commonly used local treatments lead to complete disappearance of the treated wart?
Objective: To assess the evidence for the efficacy of local treatments for cutaneous warts.
Methods: Systematic review of randomized controlled trials.
Main Outcome Measures: Total clearance of warts and adverse effects such as irritation, pain, and blistering.
Study Selection: Randomized controlled trials of any local treatment for uncomplicated cutaneous warts. All published and unpublished material was considered, with no restriction on date or language.
Results: Fifty trials provided generally weak evidence because of poor methods and reporting. The best evidence was for topical treatments containing salicylic acid. Data pooled from 6 placebo-controlled trials showed a cure rate of 75% (144 of 191) in cases compared with . . . [Full Text of this Article]
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