This Article  • Full text  • PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Citing articles on Web of Science (10)  • Contact me when this article is cited  Related Content  • Related article  • Similar articles in this journal  Topic Collections  • Dermatologic Disorders  • Dermatologic Disorders, Other  • Drug Therapy  • Drug Therapy, Other  • Alert me on articles by topic  Social Bookmarking   What's this?

Arch Dermatol. 2003;139:1061-1064.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

IN THIS ISSUE, Yoon et al¹ compare the effects of Ovide (Medicis Pharmaceutical Corporation, Phoenix, Ariz) and its active ingredient (malathion) with Nix (Pfizer/Warner-Lambert, Morris Plains, NJ) and its active ingredient (permethrin), using in vitro filter paper and contact bioassays. Lice from one location in Ecuador were compared with lice from 3 locations in the United States. In their assay, lice from a location in south Florida showed a slower response to permethrin compared with the Ecuadorian lice. In the Florida lice, Ovide and malathion showed an effect earlier than Nix or permethrin. The presence of 2 gene mutations (T929I and L932F) in permethrin-resistant lice from south Florida was confirmed by DNA sequencing. These mutations have been associated with knockdown resistance (kdr). In this assay, south Florida lice showed evidence of resistance to permethrin, but not to malathion.

Several points regarding the methods of Yoon et al¹ should be emphasized, . . . [Full Text of this Article]

Dirk M. Elston, MD
Department of Dermatology
Geisinger Medical Center
100 N Academy Ave
Danville, PA 17821
(e-mail: Delston@geisinger.edu)

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?

RELATED ARTICLE

Permethrin-Resistant Human Head Lice, Pediculus capitis, and Their Treatment
Kyong Sup Yoon, Jian-Rong Gao, Si Hyeock Lee, J. Marshall Clark, Leon Brown, and David Taplin
Arch Dermatol. 2003;139(8):994-1000.
ABSTRACT | FULL TEXT  

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

A Simple Treatment for Head Lice: Dry-On, Suffocation-Based Pediculicide
Pearlman
Pediatrics 2004;114:e275-e279.
ABSTRACT | FULL TEXT  

Scratching Your Head Over Resistant Head Lice
JWatch Pediatrics 2003;2003:10-10.
FULL TEXT  

Scratching Your Head Over Resistant Head Lice
Journal Watch Dermatology 2003;2003:1-1.
FULL TEXT