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Arch Dermatol. 2003;139:1075-1080.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Diagnosis: Ascher syndrome.

MICROSCOPIC FINDINGS AND CLINICAL COURSE

Histopathologic examination of the biopsy specimen from the patient's lower lip showed mildly hyperplastic epithelium and numerous hyperplastic salivary gland tissues in the subepithelium along with chronic inflammatory infiltrate. On clinical examination, the patient did not have thyroid enlargement, and laboratory tests revealed normal thyroid hormone levels.

DISCUSSION

Ascher syndrome is a rare entity characterized by double lip with blepharochalasis with or without nontoxic goiter. Ascher¹ originally described the features of this complete syndrome in 1920, and only 58 subsequent cases of this rare entity have been reported.² The etiology of Ascher syndrome is unclear. Most cases appear to be sporadic, although autosomal dominant inheritance has been reported.^3-4 Trauma and hormonal and allergic dysfunctions have been suggested as etiologic factors.^4-5 In 80% of cases, lip swelling appeared before 20 years of age.³ During normal fetal development, the outer portion of the lip is smooth and similar to skin and the inner . . . [Full Text of this Article]

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Arch Dermatol. 2003;139(8):1075-1080.
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