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  Vol. 139 No. 8, August 2003 TABLE OF CONTENTS
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  The Cutting Edge: Challenges in Medical and Surgical Therapeutics
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Treatment of Livedoid Vasculopathy With Low-Molecular-Weight Heparin

Report of 2 Cases

Bethany R. Hairston, MD; Mark D. P. Davis, MD; Lawrence E. Gibson, MD; Lisa A. Drage, MD
Mayo Clinic, Rochester, Minn

Arch Dermatol. 2003;139:987-990.

Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

REPORT OF CASES

CASE 1

A 23-year-old man who was otherwise healthy had a 5-year history of recalcitrant ulcers of the lower extremities. The ulcers worsened in warm weather and during periods of increased physical activity. The ulcers were painful and interfered with his participation in sports, including soccer and basketball. Shallow ulcers and crusting with stellate, porcelain-white scarring and surrounding hyperpigmentation on the lower extremities and dorsal feet were noted on examination (Figure 1).


 
Figure appears in full text version.
Figure 1. Shallow ulcers of the dorsal feet with postinflammatory hyperpigmentation and stellate scarring (patient 1 before treatment).


Noninvasive vascular testing, including continuous-wave venous Doppler imaging and measurements of the ankle-brachial index and transcutaneous oximetry (TcPO2), revealed moderately to severely reduced TcPO2 levels but no evidence of venous insufficiency. Histopathologic analysis of a skin biopsy specimen from the left ankle . . . [Full Text of this Article]

CASE 2

THERAPEUTIC CHALLENGE

SOLUTION

COMMENT



THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Livedoid Vasculopathy Associated With Plasminogen Activator Inhibitor-1 Promoter Homozygosity (4G/4G) Treated Successfully With Tissue Plasminogen Activator.
Deng et al.
Arch Dermatol 2006;142:1466-1469.
ABSTRACT | FULL TEXT  

Difficult Management of Livedoid Vasculopathy
Frances and Barete
Arch Dermatol 2004;140:1011-1011.
FULL TEXT  





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