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Treatment of Livedoid Vasculopathy With Low-Molecular-Weight Heparin
Report of 2 Cases
Bethany R. Hairston, MD;
Mark D. P. Davis, MD;
Lawrence E. Gibson, MD;
Lisa A. Drage, MD
Mayo Clinic, Rochester, Minn
Arch Dermatol. 2003;139:987-990.
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REPORT OF CASES
CASE 1
A 23-year-old man who was otherwise healthy had a 5-year history of recalcitrant ulcers of the lower extremities. The ulcers worsened in warm weather and during periods of increased physical activity. The ulcers were painful and interfered with his participation in sports, including soccer and basketball. Shallow ulcers and crusting with stellate, porcelain-white scarring and surrounding hyperpigmentation on the lower extremities and dorsal feet were noted on examination (Figure 1).
Figure appears in full text version.
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Figure 1. Shallow ulcers of the dorsal feet with postinflammatory hyperpigmentation and stellate scarring (patient 1 before treatment).
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Noninvasive vascular testing, including continuous-wave venous Doppler imaging and measurements of the ankle-brachial index and transcutaneous oximetry (TcPO2), revealed moderately to severely reduced TcPO2 levels but no evidence of venous insufficiency. Histopathologic analysis of a skin biopsy specimen from the left ankle . . . [Full Text of this Article] CASE 2
THERAPEUTIC CHALLENGE
SOLUTION
COMMENT
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ABSTRACT
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Difficult Management of Livedoid Vasculopathy
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