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Paradoxical Venous Limb Gangrene Complicating Oral Anticoagulation in a Patient With Cancer-Associated Deep Venous Thrombosis
Sophie Georgin, MD;
Jacques Pouchot, MD;
Franck Raschilas, MD;
Stéphane Barete, MD;
Dominique Lebret Lerolle, MD;
Philippe Vinceneux, MD
Arch Dermatol. 2003;139:1126-1128.
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REPORT OF A CASE
A 52-year-old white man with no significant medical history was admitted with a painful, 2-week swelling of the right calf associated with bilateral pleuritic chest pain. His temperature was 37°C, blood pressure was 110/70 mm Hg, pulse was 106/min, and respirations were 26/min. Physical examination revealed mild erythema, increased warmth, edema, and tenderness of the right calf, as well as a bilateral decrease of breath sounds, with crackles over the bases of both lung fields. The remainder of the physical examination was unremarkable. When breathing room air, the patient's arterial blood findings were the following: partial oxygen pressure, 48 mm Hg; partial carbon dioxide pressure, 38 mm Hg; and pH, 7.44. The result of a D-dimer test was positive and yielded a value of 1.0 µg/mL (normal range for plasma D-dimers, . . . [Full Text of this Article]
DIAGNOSTIC CHALLENGE
COMMENT
Centre Hospitalier Universitaire Louis Mourier, Université Xavier Bichat–Paris VII, France
THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES
Transition to an Oral Anticoagulant in Patients With Heparin-Induced Thrombocytopenia
Bartholomew
Chest 2005;127:27S-34S.
ABSTRACT
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