This Article  • Full text  • PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Contact me when this article is cited  Related Content  • Related article  • Similar articles in this journal  Topic Collections  • Diagnosis  • Dermatologic Disorders, Other  • Alert me on articles by topic

Arch Dermatol. 2004;140:121-126.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Diagnosis: Palmar myxedema.

MICROSCOPIC FINDINGS AND CLINICAL COURSE

Microscopic examination revealed a thick keratin layer with an unremarkable epidermis and a thickened dermis. Hematoxylin-eosin staining revealed collagen bundles that were separated by amorphous, faintly bluish material. There were no inflammatory cells and no increase in the number of fibroblasts in the dermis. Alcian blue staining (Figure 3) revealed extensive deposits of mucin in the upper and lower dermis, consistent with localized myxedema.

Figure appears in full text version. Figure 3.

The patient was treated with twice daily application of 0.05% clobetasol propionate cream under occlusion, with only minimal improvement.

DISCUSSION

Graves disease consists of a triad of hyperthyroidism with diffuse goiter, ophthalmopathy, and dermopathy, either alone or in combination. These 3 manifestations often run courses that are independent of each other. Onset can occur at any age, with a peak in the third and fourth decades of life. Childhood cases are uncommon, accounting for 5% of cases.¹ It is 6 to 8 times . . . [Full Text of this Article]

RELATED ARTICLE

Palmar Nodule in a Child—Quiz Case
Yong-Kwang Tay and Beng-Hock Ong
Arch Dermatol. 2004;140(1):121-126.
EXTRACT | FULL TEXT