 |
|
Hypopigmented Papules and Nodules on the Trunk and Arms—Diagnosis
Arch Dermatol. 2004;140:121-126.
|
|
| Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings. |
|
|
|
Diagnosis: Papulonodular mucinosis (PNM) associated with systemic LE.
MICROSCOPIC FINDINGS AND CLINICAL COURSE
A biopsy specimen of a papule revealed a normal epidermis with a mild perifollicular lymphocytic infiltrate (Figure 2). There was increased dermal mucin dispersed between collagen bundles, as highlighted with a colloidal iron stain. Laboratory evaluation revealed an antinuclear antibody titer equal to or greater than 1:160 (speckled pattern); a VDRL slide test result of 1:2, with a negative fluorescent treponemal antibody absorption test result; and an elevated anticardiolipin antibody titer. Complement levels were within normal limits. Serologic tests were negative for antibodies to anti-DNA, ribonuclear protein, Sm, Ro, and La. Urinalysis showed rare white and red blood cells, trace blood, and 2+ protein. A 24-hour urine study revealed nephrotic-range proteinuria at 2760 mg/d (normal,  150 mg/d). A renal ultrasound failed to show any gross abnormalities. A renal biopsy specimen revealed mesangial lupus nephritis; therefore, prednisone and azathioprine therapy was initiated. With treatment, the patient's renal function improved . . . [Full Text of this Article] DISCUSSION
 CiteULike  Connotea  Del.icio.us  Digg  Reddit  Technorati  Twitter
What's this?
RELATED ARTICLE
Hypopigmented Papules and Nodules on the Trunk and Arms—Quiz Case
Debra M. Jih and Stephen C. Somach
Arch Dermatol. 2004;140(1):121-126.
EXTRACT
| FULL TEXT
|
