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Arch Dermatol. 2004;140:121-126.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Diagnosis: Immunosuppression-induced porokeratosis and verruca vulgaris.

MICROSCOPIC FINDINGS

Microscopic examination of the edge of the plaque showed a thin epidermis with the loss of rete ridges. A cornoid lamella was seen on the surface. The epidermis below the tier of parakeratosis showed an absence of the granular layer and mild nuclear atypia, features that are diagnostic of porokeratosis. Microscopic examination of the verrucous nodule revealed a hyperplastic epidermis, hyperkeratosis, parakeratosis, and red blood cells contained within the stratum corneum. The rete ridges were elongated and fused, and there were occasional vacuolated keratinocytes, suggestive of verrucous vulgaris.

DISCUSSION

Porokeratosis, which is a progressive keratinous skin disorder, is characterized clinically by plaques of varying sizes with elevated borders. The diagnostic feature on histologic analysis is the presence of a cornoid lamella, which consists of a column of parakeratotic cells that extends through the stratum corneum, with the apex pointing away from the center of the lesion. Five clinical variants of porokeratosis . . . [Full Text of this Article]

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Arch Dermatol. 2004;140(1):121-126.
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