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Intravenous Cidofovir for Recalcitrant Verruca Vulgaris in the Setting of HIV
Chad Hivnor, MD;
James W. Shepard, MD;
Michael S. Shapiro, MD;
Carmela C. Vittorio, MD
From the University of Pennsylvania, Philadelphia.
Arch Dermatol. 2004;140:13-14.
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REPORT OF A CASE
A 34-year-old human immunodeficiency virus (HIV)seropositive man with a history of Kaposi sarcoma and ocular cytomegalovirus presented with an 8- to 10-month history of multiple, progressively enlarging verrucous papules on the proximal nail fold and the distal interphalangeal joint of the right third finger (Figure 1). His CD4 cell count was 21/µL during retroviral therapy. A clinical diagnosis of verruca vulgaris was made, and the patient was treated unsuccessfully with a variety of therapeutic modalities, including liquid nitrogen cryosurgery and hyperthermia, as well as topical imiquimod, tretinoin solution, 0.1% tazarotene gel, and 25%, 50%, and 75% podophyllin, singly and in combination. Subsequently, the patient developed molluscum contagiosum, condylomata accuminata, and periungual warts on 6 other fingers. These conditions were also treated with multiple destructive and topical modalities, without improvement.
Figure appears in full text version.
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THERAPEUTIC CHALLENGE
SOLUTION
COMMENT
THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES
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Topical cidofovir for severe warts in a patient affected by AIDS and Hodgkin's lymphoma
De Socio et al.
Int J STD AIDS 2008;19:715-716.
ABSTRACT
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