This Article  • Full text  • PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Contact me when this article is cited  Related Content  • Related article  • Similar articles in this journal  Topic Collections  • Dermatology  • Dermatologic Disorders  • Diagnosis  • Dermatologic Disorders, Other  • Alert me on articles by topic  Social Bookmarking   What's this?

Arch Dermatol. 2004;140:1275-1280.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Diagnosis: Solitary mastocytoma.

MICROSCOPIC FINDINGS AND CLINICAL COURSE

Histopathologic examination of the nodule showed a diffuse infiltration of monomorphous mononuclear cells within the upper dermis. The cells contained centrally located oval nuclei. A Giemsa stain demonstrated metachromatic purple granules in the cytoplasm (Figure 4). Immunohistochemical studies showed that the mononuclear cells were positive for common leukocyte antigen and negative for S100 protein, HMB-45, and cytokeratins. The cells were therefore identified as mast cells.

Figure appears in full text version. Figure 4.

No recurrence was noted during a 6-month follow-up period, and the patient was free of bronchial asthma during that time.

DISCUSSION

Mastocytoma may be solitary or multiple and present as a light-brown to red macule, plaque, or nodule.¹ It is rarely found in adults.² In one large series of 112 patients, most solitary mastocytomas were either present at birth or developed within the first month of life.³ Flushing, mild tenderness, and formation of bullae may occur with temperature change or trauma or . . . [Full Text of this Article]

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?

RELATED ARTICLE

A Red-Brown Plaque on the Nape—Quiz Case
I-Jing Chang, Chia-Yi Yang, Feng-Yi Sung, and Kai-Yam Ng
Arch Dermatol. 2004;140(10):1275-1280.
EXTRACT | FULL TEXT