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Reza Kafi, MD; Gary J. Fisher, PhD; Taihao Quan, PhD; Yuan Shao, PhD; Rui Wang; John J. Voorhees, MD; Sewon Kang, MD
From the University of Michigan Medical Center, Ann Arbor.

Arch Dermatol. 2004;140:1322-1324.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

REPORT OF A CASE

A 47-year-old woman presented with a 2-month history of progressive tightening of the skin on her legs. The tightening of her skin had begun 2 weeks after she was hospitalized for acute renal failure precipitated by therapy with nonsteroidal anti-inflammatory drugs. She had no history of renal disease or medical conditions that would predispose her to the organ failure. During her hospitalization, she was treated with supportive therapy only and did not require hemodialysis or peritoneal dialysis. Her renal function normalized, but the skin fibrosis continued to worsen. We initially examined her approximately 2 months after the onset of her skin disease. At the time, she had orange-red indurated plaques on both thighs and the lower part of her legs. The range of motion of her knees was . . . [Full Text of this Article]

THERAPEUTIC CHALLENGE

SOLUTION

LABORATORY METHODS

HYDROXYPROLINE MEASUREMENT

RNA ISOLATION AND QUANTITATIVE REAL-TIME REVERSE TRANSCRIPTASE–PCR

COMMENT

AUTHOR INFORMATION



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