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  Vol. 140 No. 11, November 2004 TABLE OF CONTENTS
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A Pigmented Verrucous Plaque on the Cheek—Diagnosis

Arch Dermatol. 2004;140:1393-1398.

Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Diagnosis: Nevus sebaceus with syringocystadenoma papilliferum.

MICROSCOPIC FINDINGS

Hematoxylin-eosin staining of the biopsy specimen revealed a papillated, thickened, and markedly pigmented epidermis with an increased number of mature sebaceous lobules of various sizes and shapes in the reticular dermis. The side of the biopsy specimen corresponding to the area of clinical change contained a cystlike space marked by papillations lined by 2 layers of cells, the luminal side of which revealed decapitation secretion consistent with apocrine differentiation. Within the fronds of stroma created by the papillations is an infiltrate of plasma cells.

DISCUSSION

The nevus sebaceus is a congenital hamartoma that occurs primarily on the face and scalp.1 It is a common lesion that affects males and females equally. First described by Jadassohn in 1895, nevus sebaceus is usually depicted as an alopecic, verrucous, yellowish to yellow-orange plaque. The present case is unusual in that the lesion was darkly pigmented. Nevus sebaceus can rarely be associated with the neurocutaneous . . . [Full Text of this Article]



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RELATED ARTICLE

A Pigmented Verrucous Plaque on the Cheek—Quiz Case
Gina C. Ang and Jason B. Lee
Arch Dermatol. 2004;140(11):1393-1398.
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