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A Pigmented Verrucous Plaque on the CheekDiagnosis
Arch Dermatol. 2004;140:1393-1398.
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Diagnosis: Nevus sebaceus with syringocystadenoma papilliferum.
MICROSCOPIC FINDINGS
Hematoxylin-eosin staining of the biopsy specimen revealed a papillated, thickened, and markedly pigmented epidermis with an increased number of mature sebaceous lobules of various sizes and shapes in the reticular dermis. The side of the biopsy specimen corresponding to the area of clinical change contained a cystlike space marked by papillations lined by 2 layers of cells, the luminal side of which revealed decapitation secretion consistent with apocrine differentiation. Within the fronds of stroma created by the papillations is an infiltrate of plasma cells.
DISCUSSION
The nevus sebaceus is a congenital hamartoma that occurs primarily on the face and scalp.1 It is a common lesion that affects males and females equally. First described by Jadassohn in 1895, nevus sebaceus is usually depicted as an alopecic, verrucous, yellowish to yellow-orange plaque. The present case is unusual in that the lesion was darkly pigmented. Nevus sebaceus can rarely be associated with the neurocutaneous . . . [Full Text of this Article]
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A Pigmented Verrucous Plaque on the CheekQuiz Case
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Arch Dermatol. 2004;140(11):1393-1398.
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