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"Wraparound" Technique in a 17-Month-Old Girl

Holger Bannasch, MD; Ulrich Kontny, MD; Mathias Krüger, MD; Gerd B. Stark, MD; Charlotte M. Niemeyer, MD; Mathias Brandis, MD; Raymund E. Horch, MD, PhD
From the Freiburg University Medical School, Freiburg (Drs Bannasch and Stark); University Children's Hospital, Albert-Ludwigs-University, Freiburg (Drs Kontny, Krüger, Niemeyer, and Brandis); and Medical School, Friedrich-Alexander-University, Erlangen-Nürnberg, Erlangen (Dr Horch), Germany.

Arch Dermatol. 2004;140:160-162.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

REPORT OF A CASE

A 17-month-old immunocompromised girl was admitted to the Children's University Hospital because of anemia and upper airway infection. Six months previously, she had undergone a matched unrelated bone marrow transplantation to treat juvenile myelomonocytic leukemia. Intravenous antibiotic therapy with ceftazidime was started for clinical and laboratory signs of infection.

The following day, the child developed a rapidly spreading bullous exanthema characteristic of toxic epidermal necrolysis (TEN) (Figure 1 and Figure 2) along with respiratory insufficiency requiring artificial ventilation and intensive care. A skin biopsy specimen taken from the trunk revealed a hyperkeratotic epidermis and massive epidermal necrosis with focal regeneration of the basal cell layer (Figure 3), supporting a diagnosis of TEN and ruling out staphylococcal scalded skin syndrome. Findings from . . . [Full Text of this Article]

THERAPEUTIC CHALLENGE

SOLUTION

COMMENT



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