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Arch Dermatol. 2004;140:231-236.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Diagnosis: Schopf-Schulz-Passarge syndrome.

MICROSCOPIC FINDINGS AND CLINICAL COURSE:

The biopsy specimen revealed large cystic spaces within the dermis. Two cell layers of the cystic wall were evident: outer cuboidal cells and inner columnar cells with decapitation secretion. These findings were consistent with multiple apocrine hidrocystomas. A diagnosis of Schopf-Schulz-Passarge syndrome was made. For skin cancer prophylaxis and possible treatment of both hyperkeratosis and apocrine hidrocystomas, acitretin therapy (25 mg/d) was initiated. There was minimal improvement of the hyperkertosis, and the acitretin therapy was discontinued.

DISCUSSION

In 1971, Schopf et al¹ described the syndrome of multiple eyelid apocrine hidrocystomas, palmoplantar hyperkeratosis, hypodontia, and hypotrichosis. Since then, 20 cases (13 reports) have been reported in the literature.^1-8 Multiple apocrine hidrocystomas of the eyelids have been described and can occur unrelated to this syndrome.

Schopf-Schulz-Passarge syndrome, which is characterized as a rare variant of ectodermal dysplasia,⁴ is commonly diagnosed in the second half of life.² There are more than 150 recognized forms . . . [Full Text of this Article]

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Arch Dermatol. 2004;140(2):231-236.
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