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Erythematous Plaques on the Trunk of a ManDiagnosis
Arch Dermatol. 2004;140:353-358.
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Diagnosis: Interstitial granulomatous dermatitis (IGD) with plaques.
MICROSCOPIC FINDINGS AND CLINICAL COURSE
Microscopic examination of the biopsy specimen revealed a band of granulomatous inflammation in the deep reticular dermis. Small palisaded granulomas showing collagen degeneration with focal basophilia, clusters of eosinophils, and small amounts of mucin were frequent findings. Flame figures were rare. Congestion of blood vessels was seen throughout the dermis. The subcutaneous tissue and epidermis were unremarkable.
Prednisone therapy (40 mg/d) was initiated and tapered over 3 weeks, with complete resolution of the lesions. There was still no recurrence of the lesions after 6 months.
DISCUSSION
The name IGD with plaques, which was suggested by Aloi et al,1 refers to a variant of the condition first described by Ackerman et al2 as IGD with arthritis. These relatively rare entities characterize distinct clinical conditions involving a granulomatous dermatitis commonly found in association with specific autoimmune disease or other rheumatologic complaints. Women appear to be affected more frequently than men, and . . . [Full Text of this Article]
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Arch Dermatol. 2004;140(3):353-358.
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