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Andrew L. Kaplan, MD; Linda H. Lee, MD, PhD; Russell P. Hall III, MD
Duke University Medical Center, Durham, NC

Arch Dermatol. 2004;140:353-358.

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REPORT OF A CASE

A 37-year-old white woman presented with a 1-year history of an intensely pruritic, burning eruption that was limited to her face. She stated that the itching and burning sensation would occur 1 or 2 days before the appearance of erythematous macules and small vesicles on her face. The vesicles would quickly rupture and crusts would form. She had been treated for presumed acne, but the use of topical and systemic antibiotics and topical retinoids only worsened the burning and erythema. Her medical history was notable for type 1 diabetes mellitus and iron deficiency anemia, which did not improve with oral iron supplementation. Also, a small-bowel biopsy specimen that had been obtained 2 months before presentation revealed mucosal inflammation that was consistent with gluten-sensitive enteropathy. The patient denied having current symptoms of diarrhea, bloating, cramping, abdominal discomfort, . . . [Full Text of this Article]

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Localized Facial Macules and Vesicles—Diagnosis
Arch Dermatol. 2004;140(3):353-358.
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