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In reply

Our article on SCC of the skin received media attention, including, for example, the national Swedish radio and regional Finnish newspapers.¹ We are also glad that it was noticed by scientists. However, we disagree with the proposal of Dr Grant that the observed time trends were due to tobacco smoking. We do not want to consider whether tobacco smoke is causing SCC of the skin, because the Ad Hoc Working Group of the International Agency for Research on Cancer refrained from making such a call in year 2002.² Yet, the trends of smoking prevalence among Swedish men (peaking in the 1960s) and their lung cancer incidence (peaking around 1980) show no match to the continuously increasing incidence of SCC of the skin³ (see also other references in Li et al³).

The incidence data of Stang et al from Germany show that the overall rates of invasive SCC . . . [Full Text of this Article]

Kari Hemminki, MD, PhD
Department of Biosciences at Novum
Karolinska Institute
14157 Huddinge, Sweden
(e-mail: kari.hemminki@cnt.ki.se)

Kamila Czene, PhD
Huddinge

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