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  Vol. 140 No. 4, April 2004 TABLE OF CONTENTS
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Widespread Recurrent Lichenoid Papular Eruption—Diagnosis

Arch Dermatol. 2004;140:479-484.

Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Diagnosis: Lymphomatoid papulosis (LyP).

MICROSCOPIC FINDINGS AND CLINICAL COURSE

Histopathologic examination of a papule showed a wedge-shaped dense infiltrate involving the entire dermis and composed of medium- to large-sized atypical lymphocytes. The atypical lymphocytes were admixed with histiocytes, small lymphocytes, and neutrophils and had abundant cytoplasm and prominent nucleoli. Immunohistochemical investigations revealed that the atypical lymphoid cells stained positively for anti-CD3, -CD4, -CD45RO, and -CD30 (Figure 4) antibodies. These features were consistent with type A LyP.


 
Figure appears in full text version.
Figure 4.


Methylprednisolone therapy (16 mg/d for 3 weeks) was initiated, and there was complete remission of the cutaneous lesions by the end of treatment. A few recurrent papules were observed on follow-up 4 months after the patient's initial presentation.

DISCUSSION

Lymphomatoid papulosis is a chronic recurrent papulonodular skin eruption preferentially involving the trunk and extremities, although occurrence on the face, scalp, palms, and soles, as well as mucosal involvement, has been reported.1-2 A few days after their initial appearance, cutaneous lesions . . . [Full Text of this Article]



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