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Arch Dermatol. 2004;140:609-614.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Diagnosis: Disseminated coccidioidomycosis.

MICROSCOPIC AND LABORATORY FINDINGS AND CLINICAL COURSE

Examination of hematocylin-eosin–stained sections of the biopsy specimen obtained from the plaque on the left hand revealed irregular epidermal acanthosis with an overlying crust (Figure 2). The dermis showed a mixed-cell infiltrate of neutrophils, plasma cells, lymphocytes, and foreign body giant cells. There were numerous thick-walled yeast structures containing endospores within the dermis that were visually identified as Coccidioides immitis (Figure 3). Fungal cultures from the facial plaque and the soft tissue mass involving the lower thoracic spine also yielded filamentous fungus consistent with C immitis. Amphotericin B therapy was initiated, and the patient underwent surgery for spinal cord decompression. With treatment, her skin lesions resolved completely. She initially regained functional movement of her lower extremities, but a postoperative hematoma at the surgery site caused further cord compression that led to permanent paralysis.

Figure appears in full text version. Figure 2.

Figure appears in full text version. Figure 3.

DISCUSSION

Coccidioidomycosis refers to infection by the dimorphic fungus C . . . [Full Text of this Article]

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Arch Dermatol. 2004;140(5):609-614.
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