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Multiple Skin Necrotic LesionsQuiz Case
Julia K. Soo, MBBS, MRCP;
Jonathan Bowling, MBChB, MRCP;
Raymond C. Yu, MD, FRCP
Middlesex Hospital, University College London Hospitals NHS Trust, London, England
Arch Dermatol. 2004;140:877-882.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings. |
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REPORT OF A CASE
A 50-year-old woman presented with black necrotic lesions over her left medial canthus and mastoid process. She had recently been diagnosed as having Hodgkin lymphoma and had received her first course of chemotherapy. Over the next 2 weeks, she became pancytopenic and developed sepsis. A subsequent bacterial culture of a venous access line tip yielded Staphylococcus aureus.
Despite antistaphylococcal treatment with intravenous benzylpenicillin and floxacillin, the patient's con dition deteriorated, and she was transferred to the intensive care unit at our hospital, where she received ventilatory and cardiovascular support and underwent hemofiltration. She was dependent on noradrenaline and adrenaline for inotropic support. Within 24 hours, she developed several large, black, necrotic ulcerations over the mastoid process and left medial canthus (Figure 1). Other necrotic lesions were also evident on the sole of her right . . . [Full Text of this Article]
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