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  Vol. 140 No. 9, September 2004 TABLE OF CONTENTS
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  Critical Situations: Dermatology in the Acute Care Setting
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 •HIV/AIDS
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Treatment of Recurring Cutaneous Drug Reactions in Patients With Human Immunodeficiency Virus 1 Infection

A Series of 3 Cases

Jacqueline Dolev, MD; Ilya Reyter, MD; Toby Maurer, MD

Arch Dermatol. 2004;140:1051-1053.

Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

REPORT OF CASES

CASE 1

A 41-year-old man, who was diagnosed as having human immunodeficiency virus (HIV) infection 2 weeks previously, presented to the San Francisco General Hospital emergency department, San Francisco, Calif, with acute generalized exanthematous pustulosis. The patient had begun antiretroviral therapy (ART) with stavudine, didanosine, and nelfinavir mesylate 10 days prior to presentation. His CD4 cell count was 501/µL, with a viral load of 20 copies/mL. He was admitted to the inpatient service for management. His cutaneous eruption resolved with discontinuation of all antiretroviral medications. The patient received a 10-day course of oral prednisone at 60 mg/d, which was then tapered to 30 mg/d for an additional 10 days.

One month after discharge, ART was reattempted with nevirapine, zidovudine, and lamivudine. After 10 days, he again developed acute generalized exanthematous pustulosis, which again cleared when medications were discontinued. No corticosteroid therapy was given . . . [Full Text of this Article]

CASE 2

CASE 3

THERAPEUTIC CHALLENGE

COMMENT

From the University of California, San Francisco (Drs Dolev and Maurer), and Keck School of Medicine, University of Southern California, Los Angeles (Dr Reyter)



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