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Twice-Weekly Topical Corticosteroid Therapy May Reduce Atopic Dermatitis Relapses
Hywel C. Williams, MSc, PhD, FRCP
Arch Dermatol. 2004;140:1151-1152.
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Commentary on: Twice weekly fluticasone propionate added to emollient maintenance treatment to reduce risk of relapse in atopic dermatitis: randomised, double blind, parallel group study Berth-Jones J, Damstra RJ, Golsch S, Livden JK, Van Hooteghem O, Allegra F, Parker CA BMJ. 2003;326:1367-1370
Question: How effective and safe is the addition of twice-weekly fluticasone propionate cream or ointment to regular emollient therapy for reducing relapses in people with chronic relapsing atopic dermatitis (AD)? Design: Randomized, double-blind, parallel-group study. Setting: Thirty-nine dermatology outpatient clinics in 6 European countries. Participants: People with AD, as defined by the UK Working Party's refinement of Hanifin and Rajka's diagnostic criteria,1 aged 12 to 65 years with moderate to severe disease who were experiencing a flare at study recruitment. Interventions: For the first 4-week phase of the study, all participants were given 0.05% fluticasone propionate cream or 0.005% fluticasone propionate . . . [Full Text of this Article] Comment
Queen's Medical Center, Nottingham, England
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