 |
|
Multiple Subcutaneous Nodules With Unknown Metastases to the Liver—Diagnosis
Arch Dermatol. 2005;141:93-98.
|
|
| Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings. |
|
|
|
Diagnosis: Metastatic carcinoid.
MICROSCOPIC, RADIOLOGIC, AND LABORATORY FINDINGS AND CLINICAL COURSE
Microscopic examination revealed monomorphous small round cells with eosinophilic cytoplasm in small aggregates within a fibrous stroma in the subcutis. Numerous mitotic figures, some atypical mitotic figures, and a large number of apoptotic cells were noted. Immunohistochemical staining was positive for chromogranin and synaptophysin, weakly positive for anticytokeratin 20, and negative for anticytokeratin 7. The dermis and subcutis of the tumor were strongly labeled with an AE1/AE3 anticytokeratin mixture. An infused computed tomographic scan showed diffuse hypodensities in the liver, with extensive retroperitoneal lymphadenopathy encasing the aorta and inferior vena cava. Colonoscopy revealed 1 tubular adenoma. The results of a serum chemistry profile, liver function tests, and prostate-specific antigen screening were within the normal range. A complete blood cell count was significant for anemia.
The patient was treated symptomatically with loperamide hydrochloride for diarrhea. Two months after presentation, the patient developed sepsis and subsequently died.
DISCUSSION
Carcinoid tumors are rare, slow-growing . . . [Full Text of this Article]
RELATED ARTICLE
Multiple Subcutaneous Nodules With Unknown Metastases to the Liver—Quiz Case
Michael Jude Welsch, Shail Busbey, Patricia Kurtz, and Christopher R. Shea
Arch Dermatol. 2005;141(1):93-98.
EXTRACT
| FULL TEXT
|
