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Massimo Guadagni, MD; Guido Nazzari, MD
Ospedale Civile S. Andrea La Spezia, La Spezia, Italy

Arch Dermatol. 2005;141:1490.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

The lesion presented is from the dorsal surface of the left foot of a 21-year-old Italian man. Clinical and dermoscopic images were obtained at baseline (Figure 1 and Figure 2) and 14 months later (Figure 3 and Figure 4). The lesion grew in a symmetrical manner, increasing in size about 3-fold. An evolution of dermoscopic pattern was noted. At baseline, the lesion revealed a symmetrical regular "negative" globular pattern with underlying blue-brown homogeneous pigmentation. After 14 months, the lesion revealed a confluence of the "negative" globular pattern forming dirty-tan "cobblestone" structures centrally outlined with white-blue rims. Surface scaling was also noted. The lesion was excised at this point, and the diagnosis of deep-penetrating nevus was rendered. To date, clinical images of deep-penetrating nevi are rare; to our knowledge, dermoscopic features have not been previously presented.

Figure appears in full text version. Figure 1.

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Figure appears in full text version. Figure . . . [Full Text of this Article]