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Arch Dermatol. 2005;141:1595-1600.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Diagnosis: Granulomatous slack skin.

MICROSCOPIC FINDINGS AND CLINICAL COURSE

The biopsy specimen revealed a dense nodular or diffuse cell infiltrate throughout the dermis and subcutaneous tissue. Small lymphocytes predominated, admixed with epithelioid tubercles and giant cells. Single, slightly atypical lymphocytes were seen within the epidermis. Elastolysis was observed on Weigert–van Gieson staining. Immunostaining was positive for leukocyte common antigen, CD3, and CD4.

The diagnosis of granulomatous slack skin was established, and the patient underwent further evaluation. Bone marrow aspiration showed no neoplastic infiltrate. The results of a serologic test for human T-lymphotropic virus 1 and a Sézary cell count were negative. Abdominal ultrasound showed a thickening of the abdominal wall where an indurated plaque was present, but no visceral enlargement. There was no evidence of disease spread beyond the skin.

The patient was treated with combination chemotherapy consisting of CHOP (cyclophosphamide, doxorubicin hydrochloride, vincristine sulfate, and prednisone) and bleomycin. No other lesions have appeared over 16 months of follow-up, . . . [Full Text of this Article]

DISCUSSION

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Arch Dermatol. 2005;141(12):1595-1600.
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