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Bluish Nodules on the Trunk and ArmsDiagnosis
Arch Dermatol. 2005;141:1595-1600.
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Diagnosis: Glomangioma.
MICROSCOPIC, LABORATORY, AND RADIOLOGIC FINDINGS AND CLINICAL COURSE
The skin biopsy specimen revealed irregular vascular spaces and anastomoses surrounded by a proliferation of glomus cells, which have an eosinophilic cytoplasm, rounded or sometimes pleomorphic nuclei with dense chromatin, and some evident nucleoli. The findings of a complete blood cell count, liver function tests, a fecal occult blood test, and upper gastrointestinal endoscopy were normal. Ultrasonography and computed tomography of the patients abdomen revealed a hepatic cyst in the right lobe. The painful lesions and the hepatic cyst were surgically excised. The procedures reduced the patients abdominal pain and improved her quality of life.
DISCUSSION
Glomangioma is a tumor of glomus cells, which are modified smooth muscle cells. Glomus cells are found in specialized arteriovenous shunts called Sucquet-Hoyer channels,1 which are present at acral sites, mainly the fingertips, and are involved in temperature regulation.1-3 Despite their typical acral distribution, glomus cells have also been described in bone, stomach, colon, . . . [Full Text of this Article]
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Daniela Badziak, Luis Eduardo A. M. Martins, Lysandra Ioshizumi, Fabiane Mulinari-Brenner, and Sandra Moritz
Arch Dermatol. 2005;141(12):1595-1600.
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