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  Vol. 141 No. 2, February 2005 TABLE OF CONTENTS
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Erythematous Plaques With Fever and Leukocytosis—Diagnosis

Arch Dermatol. 2005;141:263-268.

Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Diagnosis: Sweet syndrome (SS).

MICROSCOPIC FINDINGS AND CLINICAL COURSE

The skin biopsy specimen revealed a dense inflammatory cell infiltrate throughout the papillary dermis that was composed of polymorphonuclear neutrophils and lymphocytes. There was no evidence of leukocytoclastic vasculitis, such as deposits of fibrinoid material around the capillaries, disruption of the vessel structure, or extravasation of erythrocytes. Oral prednisone therapy was initiated at a dosage of 1 mg/kg. Fifteen days later, only residual erythema was noted, and the fever and conjunctivitis had subsided.

DISCUSSION

Sweet syndrome, or acute febrile neutrophilic dermatosis, was described in 1964 by Robert Douglas Sweet.1 In 1986, Su and Liu2 proposed several criteria to serve as a guide for the diagnosis of SS. In 1994, von den Driesch3 revised the criteria, classifying them into 2 categories: major and minor. The major criteria consisted of (1) the abrupt onset of tender or painful erythematous plaques or nodules occasionally with vesicles, pustules, or bullae; and (2) a predominantly neutrophilic . . . [Full Text of this Article]



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RELATED ARTICLE

Erythematous Plaques With Fever and Leukocytosis—Quiz Case
Elizabeth Guevara-Gutiérrez, Alberto Tlacuilo-Parra, and Elia Uribe-Jiménez
Arch Dermatol. 2005;141(2):263-268.
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