Diagnosis: Bacillary angiomatosis (BA).
MICROSCOPIC FINDINGS AND CLINICAL COURSE
Histopathologic examination of the biopsy specimen revealed an upper dermis that had several irregularly distributed capillaries with plump epithelioid endothelial cells. Punctate neutrophilic microabscesses were noted in an edematous stroma. There were clumps of amphophilic material in the interstitium that were were positive for bacilli on Warthin-Starry staining. The serologic titer for Bartonella henselae was positive at 1:256.
The plaques resolved, leaving postinflammatory hyperpigmentation, after a 4-week course of doxycycline (100 mg every 12 hours), and the therapy was continued for 2 more months.
COMMENT
Bacillary angiomatosis is an angioproliferative disease that was first described in 1983 by Stoler et al1 at the beginning of the AIDS epidemic. It is caused by species of weakly reactive gram-negative bacilli, B henselae and Bartonella quintana, and occurs in the late stages of HIV infection or in immunocompromised states.2 It is estimated that there are approximately 1.2 cases per 1000 HIV-positive patients.2
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