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Low-Dose Bexarotene and Low-Dose Interferon Alfa-2b for Adult T-Cell Leukemia/Lymphoma Associated With Human T-Lymphotropic Virus 1
Stephen Richardson, MD;
Jeanne B. Budgin, DVM;
Jacqueline M. Junkins-Hopkins, MD;
Carmela C. Vittorio, MD;
Jason Lee, MD;
Wallace T. Miller, Jr, MD;
Alain H. Rook, MD;
Ellen J. Kim, MD
Departments of Dermatology (Drs Richardson, Junkins-Hopkins, Vittorio, Rook, and Kim) and Radiology (Dr Miller), University of Pennsylvania Health System; Department of Dermatology, University of Pennsylvania School of Veterinary Medicine (Dr Budgin); Department of Dermatology, Thomas Jefferson Medical College (Dr Lee), Philadelphia
Arch Dermatol. 2005;141:301-304.
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REPORT OF A CASE
A 48-year-old Iranian man with a history of hypercholesterolemia and panic attacks acutely developed hand pruritus and an abdominal rash that was unresponsive to antihistamines. The rash spread across his entire trunk, and he developed chills and fatigue. He was initially diagnosed as having a possible drug reaction to fluvoxamine maleate, rofecoxib, or atorvastatin, but the rash persisted despite discontinuation of medication and a 3-week course of oral prednisone. Subsequent skin biopsy results suggested a lichenoid hypersensitivity reaction; he was given topical corticosteroids for a month, but there was no improvement.
When he presented to our clinic, he had diffuse erythema of the trunk and proximal upper extremities with numerous overlying 2- to 4-mm papules (Figure 1A). . . . [Full Text of this Article] THERAPEUTIC CHALLENGE SOLUTION
METHODS
COMMENT
AUTHOR INFORMATION
THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES
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Lin et al.
Blood 2008;112:2484-2488.
ABSTRACT
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