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  Vol. 141 No. 3, March 2005 TABLE OF CONTENTS
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Multiple Pigmented Nodules—Diagnosis

Arch Dermatol. 2005;141:389-394.

Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Diagnosis: Multiple miliary osteoma cutis.

MICROSCOPIC FINDINGS AND CLINICAL COURSE

A skin biopsy specimen obtained from the patient’s upper forehead area showed many small cavities of similar size with spherical nodules containing ossified material within the deep dermis. Other epidermal and dermal features were unremarkable. These findings, together with a history of acne, were consistent with a diagnosis of secondary multiple osteoma cutis.

The patient's active acne was treated with tetracycline and minocycline alternately over 3 years. The nodules gradually became darker, and the new lesions were blue. Because of the large size of our patient's lesions, several of them were treated with surgical incision and then removal of the osteoma in toto using a curette, with good cosmetic results.

DISCUSSION

Osteoma cutis, or the formation of bone within the skin or subcutaneous tissue, is a rare condition. It may occur de novo, as a primary disorder, eg, in Albright hereditary osteodystrophy,1 or secondary to a number of processes, including acne . . . [Full Text of this Article]


RELATED ARTICLE

Multiple Pigmented Nodules—Quiz Case
Julie S. Cronk, Nghi T. Huynh, Steven Kossard, Margot Whitfeld, and Dédée F. Murrell
Arch Dermatol. 2005;141(3):389-394.
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