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Extensive Aplasia Cutis Congenita and the Risk of Sagittal Sinus Thrombosis
Jonathan Kantor, MD, MSCE;
Albert C. Yan, MD;
Chad M. Hivnor, MD;
Paul J. Honig, MD;
Richard Kirschner, MD
Arch Dermatol. 2005;141:554-556.
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REPORT OF A CASE
A full-term 1-day-old boy weighing 3140 g was transferred to our tertiary care children’s hospital with large areas of skin defects on his scalp, trunk, and extremities. His parents were nonconsanguineous, and the results of prenatal maternal laboratory screening for human immunodeficiency virus, hepatitis B, group B streptococci, and rapid plasma reagin were negative. Intrauterine fetal death of a twin had been reported at 16 to 18 weeks of gestation. No other complications were noted during the pregnancy.
On physical examination, a full-thickness ulcer of the scalp vertex was observed extending from the anterior fontanel to the posterior fontanel in an area overlying the sagittal sinus. The defect measured 5 x 7 cm and revealed exposed dura and subcutaneous vessels (Figure 1). Two symmetric, vertically oriented, full-thickness defects, each . . . [Full Text of this Article]
DIAGNOSTIC CHALLENGE
COMMENT
AUTHOR INFORMATION
From the Hospital of the University of Pennsylvania (Drs Kantor and Hivnor) and Children’s Hospital of Philadelphia (Drs Yan, Honig, and Kirschner), University of Pennsylvania School of Medicine, Philadelphia
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