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Asymptomatic Preauricular NoduleDiagnosis
Arch Dermatol. 2005;141:633-638.
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Diagnosis: Cutaneous lymphadenoma.
MICROSCOPIC FINDINGS
Histopathologic examination revealed a well-circumscribed basaloid skin tumor that was composed of islands of cells set in a very densely fibrotic stroma. The tumor islands had a peripheral palisade of basaloid cells, with the cells in the center having larger vesicular nuclei. A heavy lymphocytic infiltrate was present within the stroma and within the tumor islands.
DISCUSSION
In 1987, Santa Cruz and Barr1 first described cutaneous lymphadenoma as a "lymphoepithelial tumour" because of its dual cellular components of lymphoid and epithelial cells. In 1991, they published a study of 13 cases of this unusual entity, renaming it cutaneous lymphadenoma.2 Cutaneous lymphadenoma is a rare benign adnexal tumor that is characterized by a peculiar pattern of lobules of epithelial basaloid cells admixed with a dense lymphocytic and histiocytic intraepithelial cell population. The tumor, which is manifested clinically by a single small, nonulcerated, slowly enlarging nodule, usually located on the head, does . . . [Full Text of this Article]
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Arch Dermatol. 2005;141(5):633-638.
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