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The possible relationship between oral lichen planus (OLP) and hepatitis C virus (HCV) infection has been studied rather extensively, but the results are rather discrepant and controversial.^1-4 The objectives of the present study were to determine the possible relationship between OLP and HCV in the Netherlands and to investigate whether screening for anti-HCV antibodies and liver enzyme levels is necessary in patients with OLP. Moreover, attempts were made to clarify the discrepant results reported in the literature on the association of OLP with HCV.

Methods

We performed a prospective study (1995-2002) of a group of 100 white patients with OLP. The control group consisted of 100 patients with psoriasis vulgaris matched for sex in clusters of 10 patients. Exclusion criteria were an age younger than 18 years, the occurrence of OLP and psoriasis vulgaris in the same patient, prior treatment with potentially hepatotoxic agents such as methotrexate, and treatment with psoralen–UV-A, . . . [Full Text of this Article]

Results

Comment

Conclusions

AUTHOR INFORMATION
Ronald Laeijendecker, MD; Theodoor H. Van Joost, MD, PhD; Bhupendra Tank, PhD; H. A. Martino Neumann, MD, PhD

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Oral Lichen Planus: Mercury and Its Kin--Reply
Laeijendecker and Tank
Arch Dermatol 2005;141:1473-1473.
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