 |
|
VIGNETTES
Association of Cutaneous Necrotizing Eosinophilic Vasculitis and Deep Vein Thrombosis in Hypereosinophilic Syndrome
|
|
| Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings. |
|
|
|
The hypereosinophilic syndrome (HES) is a heterogeneous group of conditions characterized by hypereosinophilia and organ dysfunction caused by eosinophil-mediated tissue damage.1 The most common histopathologic findings in patients with HES with papular lesions is a dermal perivascular infiltration consisting of eosinophils and mononuclear cells. True necrotizing vasculitis is rare.1 We describe herein 2 patients with HES who experienced hypereosinophilia with cutaneous necrotizing eosinophilic vasculitis in association with deep vein thrombosis (DVT) of the lower extremities.
Report of Cases
Case 1
A 58-year-old man, with a 2-month history of pruritic, erythematous to purpuric papules spreading from the legs to thighs and lower trunk, was seen in October 1996 (Figure 1A). Physical examination also disclosed right leg edema. Initial investigations revealed a total white blood cell count of 9.8 x 109/L with 41% eosinophils (4.0 x 109/L). Results from a full thrombophilia screening study and autoantibody tests were negative. Findings from stool examinations . . . [Full Text of this Article] Case 2
Comment
AUTHOR INFORMATION
Yi-Hua Liao, MD;
Yi-Wen Su, MD;
Woei Tsay, MD, PhD;
Hsien-Ching Chiu, MD
THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES
Eosinophils are a major intravascular location for tissue factor storage and exposure
Moosbauer et al.
Blood 2007;109:995-1002.
ABSTRACT
| FULL TEXT
Superficial Venous Thrombophlebitis as the Initial Manifestation of Hypereosinophilic Syndrome: Study of the First 3 Cases
Terrier et al.
Arch Dermatol 2006;142:1606-1610.
ABSTRACT
| FULL TEXT
|
