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Adalimumab for Treatment of Cutaneous Sarcoidosis
Michael P. Heffernan, MD;
David I. Smith, MD
Washington University School of Medicine, St Louis, Mo
Arch Dermatol. 2006;142:17-19.
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REPORT OF A CASE
The patient, a 46-year-old black woman, was referred to the dermatology clinic at Washington University, St Louis, Mo, for evaluation of reddish-purple nodules on her face and shins. The patient’s medical history was significant for hypothyroidism and an arrhythmia. Findings from a punch biopsy from her right nasal ala showed confluent granulomas with central caseous necrosis in the dermis. Findings from a wedge biopsy specimen from her right shin showed granulomas in the dermis and subcutis with necrotizing foci. Acid-fast bacteria and Giemsa stains of both specimens were negative for mycobacteria and fungal organisms. Because of continued concern that she had an infection, an excisional biopsy specimen from the right leg was taken. Tissue culture for bacteria, mycobacteria, and fungi failed to grow any organisms. Histologic examination of this specimen revealed a septal panniculitis consistent with a diagnosis of erythema nodosum. Despite . . . [Full Text of this Article]
THERAPEUTIC CHALLENGE
SOLUTION
COMMENT
AUTHOR INFORMATION
THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES
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Updated consensus statement on biological agents for the treatment of rheumatic diseases, 2007
Furst et al.
Ann Rheum Dis 2007;66:iii2-iii22.
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