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Successful Treatment of Mucous Membrane Pemphigoid With Infliximab
Michael P. Heffernan, MD;
Danette D. Bentley, MD
Divisions of Dermatology, Wright State University School of Medicine, Dayton, Ohio (Dr Heffernan), and Washington University, St Louis, Mo (Dr Bentley)
Arch Dermatol. 2006;142:1268-1270.
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REPORT OF A CASE
Our patient was diagnosed with cicatricial pemphigoid (CP) in 2001. She demonstrated classic clinical findings and underwent biopsies that supported this diagnosis. She unfortunately experienced severe CP involving both of her eyes, oral mucosa, pharyngeal mucosa, and esophagus. Her left eye was seriously affected early in the course of her disease. She experienced significant scarring of the cornea of her left eye as well as of both its upper and lower eyelids, resulting in symblepharon and complete blindness of this eye. She has also endured considerable disease in her right eye and has undergone multiple corneal transplants of this eye (in March 2001, September 2004, January 2005, and April 2005). The most recent corneal transplant in April 2005 was performed emergently for a ruptured corneal ulcer. Our dermatology team was consulted during the patient's hospitalization for this event.
At our initial encounter . . . [Full Text of this Article]
THERAPEUTIC CHALLENGE
SOLUTION
COMMENT
AUTHOR INFORMATION
THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES
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p38 MAPK Signaling in Oral-related Diseases
Patil and Kirkwood
J. Dent. Res. 2007;86:812-825.
ABSTRACT
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