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  Vol. 142 No. 10, October 2006 TABLE OF CONTENTS
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Painful Plaque on a Young Man—Diagnosis

Arch Dermatol. 2006;142:1351-1356.

Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Diagnosis: Eccrine angiomatous hamartoma (EAH).

MICROSCOPIC FINDINGS AND CLINICAL COURSE

Histopathologic examination of the excised specimen revealed a collection of well-differentiated eccrine ducts and glands mixed with dilated and collapsed vascular spaces, as well as abundant adipose tissue and epidermal inclusion cysts. The lesion was excised without complication, and there has been no recurrence to date.

DISCUSSION

Eccrine angiomatous hamartoma is an uncommon benign tumor that usually occurs on the lower extremities and is congenital or appears in early childhood. The lesions are usually nodular and solitary and can be painful. The pain may be due to proliferation of nerve tissue. The lesions may also demonstrate hyperhidrosis, especially when they are manipulated.

Pilar and adipose structures are uncommon features of EAH.1-3 The secretory eccrine components stain with S100 protein, carcinoembryonic antigen, epithelial membrane antigen, and CAM 5.2. The ductal components stain strongly for carcinoembryonic antigen and cytokeratin 1 and weakly for epithelial membrane antigen. The vascular structures stain with anti–Ulex . . . [Full Text of this Article]


RELATED ARTICLE

Painful Plaque on a Young Man—Quiz Case
Edward George Butler, II, Damian P. Derienzo, and Robert Harford
Arch Dermatol. 2006;142(10):1351-1356.
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