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  Vol. 142 No. 12, December 2006 TABLE OF CONTENTS
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Growth Rate, Early Detection, and Prevention of Melanoma

Melanoma Epidemiology Revisited and Future Challenges

Arch Dermatol. 2006;142:1638-1640.

Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

In this issue of the ARCHIVES, Liu et al1 make a significant contribution to the understanding of differential growth rates of melanomas. Using the Breslow index as a surrogate for tumor growth, they find that approximately one third of melanomas are rapidly growing melanomas. These fast-growing tumors are usually thick, occur mainly in elderly patients, and from a clinical point of view are symmetrical.

The notion that tumor growth is not the same in each melanoma subtype is intuitive and empirical. The classic distinction of melanomas into superficial spreading, acrolentiginous, lentigo maligna, and nodular subtypes is subject to debate.2 These classic histogenetic types are not an independent prognostic factor, and many melanomas do not fit into these categories.3-4

The genesis and progression of melanoma have been compared with an eclipse5 in which successive biological phenomena occur, including the loss of cell cycle regulation, capacity of intraepidermal tumor spread, . . . [Full Text of this Article]

HOW FREQUENT ARE FAST-GROWING MELANOMAS, AND HOW CAN WE RECOGNIZE THEM?


HOW DO THEIR FINDINGS FIT INTO OUR UNDERSTANDING OF MELANOMA EPIDEMIOLOGY?

WHAT IS THE IMPACT OF THE EXISTENCE OF FAST-GROWING MELANOMAS ON DETECTION AND PREVENTION?

AUTHOR INFORMATION
Dan Lipsker, MD, PhD



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RELATED LETTERS

Fast-Growing and Slow-Growing Melanomas
Giuseppe Argenziano, Iris Zalaudek, and Gerardo Ferrara
Arch Dermatol. 2007;143(6):802-803.
EXTRACT | FULL TEXT  

Fast-Growing and Slow-Growing Melanomas—Reply
John W. Kelly, Grant A. McArthur, Rory Wolfe, John F. Thompson, and Wendy Liu
Arch Dermatol. 2007;143(6):803-804.
EXTRACT | FULL TEXT  

Increasing Ratio of Thin to Thick Melanoma Lesions: Pathogenesis and Early Detection of This Cancer
Jean-Claude Bystryn
Arch Dermatol. 2007;143(6):804.
EXTRACT | FULL TEXT  

Increasing Ratio of Thin to Thick Melanoma Lesions: Pathogenesis and Early Detection of This Cancer—Reply
Dan Lipsker
Arch Dermatol. 2007;143(6):804-805.
EXTRACT | FULL TEXT  

RELATED ARTICLE

Rate of Growth in Melanomas: Characteristics and Associations of Rapidly Growing Melanomas
Wendy Liu, John P. Dowling, William K. Murray, Grant A. McArthur, John F. Thompson, Rory Wolfe, and John W. Kelly
Arch Dermatol. 2006;142(12):1551-1558.
ABSTRACT | FULL TEXT  


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Three Roots of Melanoma
Zalaudek et al.
Arch Dermatol 2008;144:1375-1379.
FULL TEXT  

Utility of Lesion Diameter in the Clinical Diagnosis of Cutaneous Melanoma
Abbasi et al.
Arch Dermatol 2008;144:469-474.
ABSTRACT | FULL TEXT  

Fast-Growing and Slow-Growing Melanomas
Argenziano et al.
Arch Dermatol 2007;143:802-803.
FULL TEXT  

Fast-Growing and Slow-Growing Melanomas--Reply
Kelly et al.
Arch Dermatol 2007;143:803-804.
FULL TEXT  

Increasing Ratio of Thin to Thick Melanoma Lesions: Pathogenesis and Early Detection of This Cancer
Bystryn
Arch Dermatol 2007;143:804-804.
FULL TEXT  

Increasing Ratio of Thin to Thick Melanoma Lesions: Pathogenesis and Early Detection of This Cancer--Reply
Lipsker
Arch Dermatol 2007;143:804-805.
FULL TEXT  





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