Diagnosis: Blastomycosis-like pyoderma.
MICROSCOPIC FINDINGS AND CLINICAL COURSE
The biopsy specimen revealed pseudoepitheliomatous hyperplasia and a neutrophil-predominant dermal inflammatory infiltrate with microabscesses in the dermis and epidermis. Stains were negative for bacteria and fungi. Cultures of the punch biopsy specimen yielded methicillin-resistant Staphylococcus aureus. Tissue cultures were negative for mycobacterial and fungal organisms.
Oral cephalexin was administered. The plaques were covered with nonadherent sterile dressings. Within 2 days, the pustules had resolved and the erythema, exudation, and pain had diminished. Cephalexin therapy was continued in view of the excellent therapeutic response despite antimicrobial sensitivities showing resistance. Within 3 weeks, only mild erythema with slight scaling remained.
DISCUSSION
Blastomycosis-like pyoderma is a rare disorder that is characterized by painful, pustule-studded, verrucous, exudative plaques with raised, irregular borders. It was first described in 1903 as pseudoépithéliomas cutanés, but recognition of its clinical similarity to cutaneous blastomycosis led to the term mycosis-like pyoderma and then finally to blastomycosis-like pyoderma.1 . . . [Full Text of this Article]