This Article  • Full text  • PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Topic Collections  • Dermatologic Disorders  • Diagnosis  • Sarcoidosis  • Alert me on articles by topic  Social Bookmarking   What's this?

Arch Dermatol. 2006;142:1643-1648.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Diagnosis: Sarcoidosis.

MICROSCOPIC FINDINGS

Microscopic examination of the skin biopsy specimen revealed aggregates of noncaseating granulomas in the dermis, consistent with sarcoidosis. No foreign material was identified. A portion of the epidermis overlying and adjacent to the granulomas showed significant vacuolar alteration of the basilar layer, with formation of numerous Civatte bodies, indicating an associated interface dermatitis.

DISCUSSION

The clinical manifestations of sarcoidosis are numerous and variable. The classic presentation of cutaneous sarcoidsis includes macules and papules that demonstrate an "apple-jelly" color on diascopy. Sarcoidosis appearing in scars and lupus pernio are other common manifestations. Less common morphological forms include annular, nodular, ichthyosiform, psoriasiform, verrucous, hypopigmented, and atrophic. Sarcoidosis may present as erythroderma or alopecia.¹

Sarcoidosis, especially the cutaneous form, is a rare entity in India. While little has been reported on cutaneous sarcoidosis in India, it is known that darker skin types more frequently display atypical features of the entity, including hypopigmented macules.² These . . . [Full Text of this Article]

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati     What's this?