Diagnosis: Sarcoidosis.
MICROSCOPIC FINDINGS
Microscopic examination of the skin biopsy specimen revealed aggregates of noncaseating granulomas in the dermis, consistent with sarcoidosis. No foreign material was identified. A portion of the epidermis overlying and adjacent to the granulomas showed significant vacuolar alteration of the basilar layer, with formation of numerous Civatte bodies, indicating an associated interface dermatitis.
DISCUSSION
The clinical manifestations of sarcoidosis are numerous and variable. The classic presentation of cutaneous sarcoidsis includes macules and papules that demonstrate an "apple-jelly" color on diascopy. Sarcoidosis appearing in scars and lupus pernio are other common manifestations. Less common morphological forms include annular, nodular, ichthyosiform, psoriasiform, verrucous, hypopigmented, and atrophic. Sarcoidosis may present as erythroderma or alopecia.1
Sarcoidosis, especially the cutaneous form, is a rare entity in India. While little has been reported on cutaneous sarcoidosis in India, it is known that darker skin types more frequently display atypical features of the entity, including hypopigmented macules.2 These . . . [Full Text of this Article]