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  Vol. 142 No. 12, December 2006 TABLE OF CONTENTS
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VIGNETTES
Pigmented Purpuric Dermatosis Associated With Creatine Supplementation

Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Report of a Case

An otherwise healthy 28-year-old man with a history of allergic rhinitis was seen for a rash of the legs. The lesions had developed intermittently during the past 3 months. Physical examination revealed six 1- to 2-cm annular, erythematous, nonscaly plaques of the thighs with a cayenne pepper–like appearance, suggesting a pigmented purpuric dermatosis (PPD) (Figure 1). A biopsy specimen of a lesion revealed histologic findings consistent with PPD (Figure 2). Microscopically, there was a superficial, perivascular, lymphocytic infiltrate with extravasation of erythrocytes in the papillary dermis. The patient was a weightlifter and had been taking a commercial dietary supplement containing creatine and hydroxymethylbutyrate for the past 6 years. It was decided that the patient should discontinue taking this supplement, and within 2 weeks, the lesions had resolved leaving some mild postinflammatory changes. A rechallenge with the supplement was not undertaken.


 
Figure appears in full text version.
Figure 1. Clinical features of pigmented . . . [Full Text of this Article]



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AUTHOR INFORMATION
Joe A. Chorny, MD; Joel Cohen, MD



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