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William L. Fangman, MD; M. Angelica Selim, MD; John C. Murray, MD
Duke University Medical Center, Durham, NC

Arch Dermatol. 2006;142:235-240.

	Since this article does not have an abstract, we have provided the first 146 words of the full text and any section headings.

REPORT OF A CASE

A 31-year-old African American woman presented for evaluation of an increasing number of diffuse, asymptomatic, hypopigmented macules of 2 to 3 years' duration. She had no history of inflammatory lesions, but she did have an 18-year history of hyperkeratotic papules, which were predominantly distributed on her forehead (Figure 1) and upper trunk area. The hyperkeratotic papules were associated with pruritus that worsened when the ambient temperature increased. There was no family history of a similar eruption. A histopathologic section from an abdominal hypopigmented macule was stained with MART-1 (melanoma antigen recognized by T cells) (Figure 2 [the clinical hypopigmentation is on the left side]). A section of an abdominal hyperkeratotic papule was sent for routine histopathologic analysis (Figure 3).

Figure appears in full text version. Figure 1.

Figure appears in full text version. Figure 2.

Figure appears in full text version. Figure 3.

What is your diagnosis?

SECTION EDITOR: MICHAEL E. MING, MD

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Diffuse Hypopigmented Macules—Diagnosis
Arch Dermatol. 2006;142(2):235-240.
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