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  Vol. 142 No. 3, March 2006 TABLE OF CONTENTS
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Erosive Velvety Lesion on the Vulva—Diagnosis

Arch Dermatol. 2006;142:385-390.

Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Diagnosis: Vulvar basal cell carcinoma (BCC).

MICROSCOPIC FINDINGS AND CLINICAL COURSE

Histopathologic examination of the biopsy specimen demonstrated many tumor nests with a peripheral palisading arrangement in the upper and middle dermis. The tumor cells were small and had indistinct cytoplasmic borders and oval, basophilic, vesicular nuclei. These histopathologic findings were consistent with BCC. The patient and her family refused any further examinations and therapy, probably because of her age.

DISCUSSION

Basal cell carcinoma, which is the most common malignant neoplasm of the skin, commonly arises on the face. Ono1 found that 85% of BCCs in ethnic Japanese patients are pigmented and therefore require differentiation from malignant melanoma. Clinical diagnosis is not difficult in cases of BCC in which the tumor shows the typical black appearance, but in cases involving a nonpigmented BCC on an unusual site, the diagnosis is likely to depend on the findings of histologic examination.

Our patient was originally thought to have extramammary Paget disease because the vulva . . . [Full Text of this Article]


RELATED ARTICLE

Erosive Velvety Lesion on the Vulva—Quiz Case
Takane Suda and Hiroshi Kakinuma
Arch Dermatol. 2006;142(3):385-390.
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