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Expanding the Role of Topical Retinoids?

Arch Dermatol. 2006;142:638-640.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

In this issue of the ARCHIVES, Thiboutot et al¹ and Leyden et al² provide the first rigorous clinical data on the suitability of topical retinoid monotherapy as maintenance treatment for acne vulgaris. For many dermatologists, the concept that topical retinoids alone may be effective in the maintenance phase of therapy for inflammatory acne may represent a substantial departure from their traditional thinking about the role of this class of medications in the treatment armamentarium. While establishing the clinical efficacy of topical retinoids in this setting presents new challenges to current concepts of acne trial design, expanding the use of this class of medications in acne maintenance therapy may help to significantly reduce antibiotic overuse.

Since the introduction of topical retinoids, most dermatologists have been trained to use them almost exclusively for the treatment of predominantly comedonal acne vulgaris. For many years, a common practice both in the United . . . [Full Text of this Article]

AUTHOR INFORMATION
Lee T. Zane, MD, MAS

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