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Arch Dermatol. 2006;142:641-646.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Diagnosis: Spindle cell hemangioma.

MICROSCOPIC FINDINGS

Microscopic examination revealed a circumscribed, dermal-based vascular tumor that extended focally into the subcutaneous fat. The lesion showed an admixture of smaller-caliber thick-walled vessels, larger cavernous vessels, and proliferating spindled cells. In areas of small vessels, the endothelial lining appeared somewhat plump, with hyperchromatic nuclei and minimal cytoplasm. Some of the larger vessels contained fibrin thrombi. Mitotic activity was inconspicuous. A Warthin-Starry stain was negative for bacteria. The results of a human herpesvirus 8 stain were also negative.

DISCUSSION

Spindle cell hemangioma, originally termed spindle cell hemangioendothelioma, was previously regarded as low-grade angiosarcoma based on the observation that 1 case in a series of 26 had metastasized to a regional lymph node.¹ However, this single case had recurred locally 19 times and had been irradiated, suggesting that malignant transformation might have been a complication of radiation therapy. Results of larger studies with longer follow-up indicated that this type of tumor . . . [Full Text of this Article]

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Arch Dermatol. 2006;142(5):641-646.
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