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Abdominal Plaque in a 10-Day-Old BoyDiagnosis
Arch Dermatol. 2006;142:641-646.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings. |
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Diagnosis: Kaposiform hemangioendothelioma with Kasabach-Merritt phenomenon (KMP).
MICROSCOPIC FINDINGS AND CLINICAL COURSE
Hematoxylin-eosinstained sections of the punch biopsy specimen showed a vascular proliferation within the dermis that was composed of spindled endothelial cells diffusely infiltrating the collagen fibers as well as areas with a more lobular architecture. Rare mitotic figures were seen.
Our patient received intravenous methylprednisolone and vincristine therapy in the hospital. Within 3 weeks, he was discharged with instructions to return for weekly infusions of vincristine and tapering doses of methylprednisolone. At his most recent follow-up, 5 months after initial presentation, he was clinically stable with no significant bleeding episodes. The tumor has showed partial reduction in size as a result of treatment.
DISCUSSION
Rarely, vascular tumors may be complicated by KMP, which is a consumptive coagulopathy that typically presents in the first few weeks of life (mean age at onset, 7 weeks). It is characterized by the triad of hemangioma, thrombocytopenia, and coagulopathy. The underlying hemangioma may be an obvious . . . [Full Text of this Article]
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Abdominal Plaque in a 10-Day-Old BoyQuiz Case
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Arch Dermatol. 2006;142(5):641-646.
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