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A 42-year-old white man presented for a second opinion of asymptomatic lesions on his face and hands that had been present for 2 years. Physical examination revealed orange-brown coalescing translucent papules on the bilateral temples and zygomatic cheeks (Figure 1) as well as skin-colored papules on the dorsal hands. Histopathologic examination of lesional skin from the left zygoma and left dorsal hand showed expansion of the upper dermis by amphophilic amorphous material (Figure 2). The dermatopathologist's initial impression was that the patient had nodular amyloidosis. However, he agreed that the diagnosis was colloid milium after reading the clinician's impression.

Figure appears in full text version. Figure 1. Confluent orange papules on the zygoma.

Figure appears in full text version. Figure 2. Lesional skin specimen on histopathologic examination shows amphophilic waxy nodules in the upper dermis (hematoxylin-eosin, original magnification, x50).

Colloid milium is typically divided into adult, juvenile, nodular, and pigmented subtypes. Adult colloid milium is the most . . . [Full Text of this Article]

AUTHOR INFORMATION
Anupam M. Desai, MD; Josie A. Pielop, MD; Megan J. Smith-Zagone, MD; Sylvia Hsu, MD