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Atrophic Congenital Lesion on the BackDiagnosis
Arch Dermatol. 2006;142:921.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings. |
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Diagnosis: Medallionlike dermal dendrocyte hamartoma.
MICROSCOPIC FINDINGS
Histologically, the epidermis was focally atrophic, and the dermis was increased in thickness, showing a spindle-cell proliferation that extended into the subcutaneous fat and included a reduction of cutaneous adnexa as well as a moderate collagenous component. A mild increase in perivascular mast cells was also noted.
Immunohistochemical findings included CD34 and factor XIIIa immunoreactivity in a majority of spindle cells, suggesting a dermal dendritic cell phenotype of the proliferating population. The immunoreactivity of S100 protein and CD68 was not significant. An orcein stain demonstrated that elastic fibers were diminished.
DISCUSSION
Medallionlike dermal dendrocyte hamartoma is a recently reported entity.1 It has been described in female patients as a single asymptomatic, medallion-shaped, congenital lesion. In all cases, the lesions were round, oval, or triangular and several centimeters in greatest dimension, with well-defined borders and a brownish erythematous color. They were covered with atrophic skin that was pliable and wrinkled easily. Veins . . . [Full Text of this Article]
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Arch Dermatol. 2006;142(7):921.
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